RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
Dlk1
RNA ID
RNA Type
mRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
cell proliferation assays
Target
DLK1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Deletion of delta-like 1 homologue accelerates fibroblast-myofibroblast differentiation and induces myocardial fibrosis
Year
2019
Function
An inhibitory role of DLK1 of cardiac fibroblast-to-myofibroblast differentiation by interfering with TGF-beta/smad-3 signalling in the myocardium.